In vivo bioavailability and therapeutic assessment of host-guest inclusion phenomena for the hydrophobic molecule etodolac: pharmacodynamic and pharmacokinetic evaluation
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The aim of present investigation was 1) to evaluate the in vivo bioavailability of an Etodolac (ETD)-Î-cyclodextrin (Î-CD) inclusion complex system prepared by kneading and spray drying techniques in rats, 2) to study the pharmacodynamic parameters in variou... ...