Iridium Catalyzed Hydro-hydroxyalkylation of Butadiene: Carbonyl Crotylation
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Exposure of alcohols 1a-1i to butadiene in the presence of a cyclometallated iridium catalyzed derived from allyl acetate, 4-methoxy-3-nitrobenzoic acid and BIPHEP (2,2'-bis(diphenylphosphino)biphenyl) results in hydrogen transfer to generate aldehyde-allyliri... ...