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A review of the sirtuin system, its clinical implications, and the potential role of dietary activators like resveratrol: part 1

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The silent information regulator (SIR) genes (sirtuins) comprise a highly conserved family of proteins, with one or more sirtuins present in virtually all species from bacteria to mammals. In mammals seven sirtuin genes - SIRT1 to SIRT7 - have been identified.... ...