1α,25-dihydroxyvitamin D₃ rapidly modulates Ca(2+) influx in osteoblasts mediated by Ca(2+) channels
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The biologically active form of vitamin D, 1α,25-dihydroxy vitamin D₃ (VD), regulates the synthesis of the bone Ca-binding proteins osteocalcin and osteopontin. The actions of VD are mediated through the vitamin D receptor (VDR). Liganded VDR heterodimerizes... ...