The four trypanosomatid eIF4E homologues fall into two separate groups, with distinct features in primary sequence and biological properties
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Translation initiation in eukaryotes requires eIF4E, the cap binding protein, which mediates its function through an interaction with the scaffolding protein eIF4G, as part of the eIF4F complex. In trypanosomatids, four eIF4E homologues have been described but... ...