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Results of a safety initiative for patients on concomitant amiodarone and simvastatin therapy in a Veterans Affairs medical center

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Background: The FDA revised the labels of amiodarone and simvastatin in 2002 to warn of increased risk of rhabdomyolysis, the most severe form of myopathy, when the 2 drugs are taken concomitantly in doses greater than 20 milligr... ...