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Homocysteine enhances transmigration of rat monocytes through a brain capillary endothelial cell monolayer via ICAM-1

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Increased homocysteine (Hcy) levels contribute to a variety of cardiovascular and cerebrovascular diseases including stroke and Alzheimer's disease. Recent data has shown that elevated levels of Hcy can lead to the blood-brain barrier (BBB) dysfunction and act... ...