Association of thymidylate synthase enhancer region polymorphisms with thymidylate synthase activity in vivo
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Two known polymorphisms in the 5' enhancer region (ER) of the thymidylate synthase (TS) gene, a variable number of tandem repeats of a 28 bp sequence (2R/3R) and a further G>C single nucleotide substitution within the repeats, result in genotypes with 0-5 func... ...
