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Association of the histidine-triad nucleotide-binding protein-1 (HINT1) gene variants with nicotine dependence

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The histidine triad nucleotide-binding protein-1 gene (HINT1) is implicated in schizophrenia and in the behavioral effects of morphine and amphetamine. Because nicotine dependence (ND) is highly comorbid with schizophrenia and other substance abuse, we examine... ...