CCR5 antagonists: host-targeted antiviral agents for the treatment of HIV infection, 4 years on
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The chemokine coreceptor 5 (CCR5) antagonists are antiretroviral agents with an extracellular, host-targeted mechanism of action against HIV. Maraviroc, the first-in-class CCR5 antagonist, received regulatory approval in 2007, becoming the first oral antiretro... ...
