Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity
{{output}}
Neurotoxicity is one of the most relevant dose-limiting toxicities of the anticancer drug paclitaxel. It exhibits substantial interindividual variability of unknown molecular basis, and represents one of the major challenges for the improvement of paclitaxel t... ...