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Mitochondria-targeted antioxidant effects of S(-) and R(+) pramipexole

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Background: Pramipexole exists as two isomers. The S(-) enantiomer is a potent D3/D2 receptor agonist and is extensively used in the management of PD. In contrast, the R(+) enantiomer is virtually devoid of any of the DA agonist ... ...