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Juvenile myelomonocytic leukemia: epidemiology, etiopathogenesis, diagnosis, and management considerations

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Juvenile myelomonocytic leukemia (JMML) is a rare hematopoietic malignancy of early childhood with features characteristic of both myelodysplastic and myeloproliferative disorders. Recent studies clearly show that the deregulated activation of the RAS signalin... ...