Human molecular genetics. 2009 Dec 15;18(24):4781-90. doi: 10.1093/hmg/ddp441 Q23.22025
Chromosomal and genetic alterations in human hepatocellular adenomas associated with type Ia glycogen storage disease
与I型糖原贮积病相关的肝细胞腺瘤的染色体和基因改变 翻译改进
Priya S Kishnani 1, Tzu-Po Chuang, Deeksha Bali, Dwight Koeberl, Stephanie Austin, David A Weinstein, Elaine Murphy, Ying-Ting Chen, Keri Boyette, Chu-Hao Liu, Yuan-Tsong Chen, Ling-Hui Li
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作者单位
1 Division of Medical Genetics, Duke University Medical Center, Durham, NC 27710, USA.
DOI: 10.1093/hmg/ddp441 PMID: 19762333
摘要 Ai翻译
Hepatocellular adenoma (HCA) is a frequent long-term complication of glycogen storage disease type I (GSD I) and malignant transformation to hepatocellular carcinoma (HCC) is known to occur in some cases. However, the molecular pathogenesis of tumor development in GSD I is unclear. This study was conducted to systematically investigate chromosomal and genetic alterations in HCA associated with GSD I. Genome-wide SNP analysis and mutation detection of targe... ...点击完成人机验证后继续浏览
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