Memory deficits in APP23/Abca1+/- mice correlate with the level of Aβ oligomers
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ABCA1, a member of the ATP-binding cassette family of transporters, lipidates ApoE (apolipoprotein A) and is essential for the generation of HDL (high-density lipoprotein)-like particles in the CNS (central nervous system). Lack of Abca1 increases amyloid depo... ...
