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Krüppel-like factor 4 represses transcription of the survivin gene in esophageal cancer cell lines

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Aberrant expression of survivin has been shown to be regulated at the transcription level in cancer cells. In this study, we demonstrate that there are six putative binding sites of Krüppel-like factor 4 (KLF4) within the 2000-bp region upstream of the transc... ...