New insights on the neuroprotective role of sterols and sex steroids: the seladin-1/DHCR24 paradigm
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In 2000 a new gene, i.e. seladin-1 (for selective Alzheimer's disease indicator-1) was identified and found to be down regulated in vulnerable brain regions in Alzheimer's disease. Seladin-1 was considered a novel neuroprotective factor, because of its anti-ap... ...