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GD3 synthase overexpression enhances proliferation and migration of MDA-MB-231 breast cancer cells

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The disialoganglioside G(D3) is an oncofetal marker of a variety of human tumors including melanoma and neuroblastoma, playing a key role in tumor progression. G(D3) and 9-O-acetyl-G(D3) are overexpressed in approximately 50% of invasive ductal breast carcinom... ...