[The role of DNA methylation and histone modifications in structural maintainance of heterochromatin domains (chromocenters)]
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The effects of DNA methylation inhibitor 5-azacytidine (5-aza-C) and histone acetylation inhibitor trichostatine A (TSA) on the structure of pericentric heterochromatin in cultured mouse cells (L929) has been studied. After 48 h of 5-aza-C treatment, about 85%... ...
