FoxO1 mediates PTEN suppression of androgen receptor N- and C-terminal interactions and coactivator recruitment
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FoxO (mammalian forkhead subclass O) proteins are transcription factors acting downstream of the PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor. Their activity is negatively regulated by AKT-mediated phosphorylation. Our previo... ...
