An update on pharmacogenomics in rheumatoid arthritis with a focus on TNF-blocking agents
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TNFalpha is a proinflammatory cytokine, which is crucial in the pathogenesis of rheumatoid arthritis (RA). In recent years, biological therapies which block the damaging effects of TNFalpha on synovium and cartilage have been developed. TNF antagonists, such a... ...
