Pharmacokinetics of buccal mucosal administration of fentanyl in a carboxymethylcellulose gel compared with IV administration in dogs
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The pharmacokinetics of fentanyl administrated IV (0.01 mg/kg) and in a carboxymethylcellulose gel (0.05 mg/kg) applied to the buccal mucosa of six healthy adult medium- to large-breed dogs was evaluated. At 5 minutes after transmucosal (TM) administration, se... ...