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Analysis of the human cytomegalovirus pp65-directed T-cell response in healthy HLA-A2-positive individuals

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Human cytomegalovirus (HCMV) is contained by T-lymphocyte responses focused towards the major tegument protein pp65. To systematically identify T-cell epitopes, we applied the following strategy: 441 overlapping 15mer peptides spanning the entire HCMV pp65 ant... ...