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High-throughput screening of a 100,000-compound library for inhibitors of influenza A virus (H3N2)

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Using a highly reproducible and robust cell-based high-throughput screening (HTS) assay, the authors screened a 100,000-compound library at 14- and 114-microM compound concentration against influenza strain A/Udorn/72 (H3N2). The "hit" rates (>50% inhibition o... ...