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Behavioural brain research. 2008 Nov 21;193(2):289-97. doi: 10.1016/j.bbr.2008.06.012 Q22.32025

Dose dependence and therapeutic window for the neuroprotective effects of curcumin in thromboembolic model of rat

姜黄素对血栓栓塞性卒中模型神经保护作用的有效剂量范围及治疗窗研究 翻译改进

Preeti Dohare  1, Puja Garg, Vikas Jain, Chandishwar Nath, Madhur Ray

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  • 1 Division of Pharmacology, Central Drug Research Institute, Lucknow 226001, India.

    • DOI: 10.1016/j.bbr.2008.06.012 PMID: 18611416

    摘要 Ai翻译

    Curcumin (diferuloylmethane), an active ingredient of turmeric, obtained from the powdered rhizomes of Curcuma longa Linn., has been traditionally recognized for treatment of several diseases. To evaluate the potential clinical use of curcumin, we determined the dose dependence of its effects in the therapeutic window and of the neuroprotective efficacy in a cerebral thromboembolic model of the rat. Rats were subjected to occlusion of the middle cerebral a... ...点击完成人机验证后继续浏览
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    期刊名：Behavioural brain research

    缩写：BEHAV BRAIN RES

    ISSN：0166-4328

    e-ISSN：1872-7549

    IF/分区：2.3/Q2

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    Dose dependence and therapeutic window for the neuroprotective effects of curcumin in thromboembolic model of rat