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Behavioural brain research. 2008 Nov 21;193(2):298-305. doi: 10.1016/j.bbr.2008.06.010 Q22.32025

The cannabinoid CB1 receptor inverse agonist AM 251 and antagonist AM 4113 produce similar effects on the behavioral satiety sequence in rats

cannabinoid CB1受体拮抗剂AM 4113和反激动剂AM 251对大鼠摄食行为的类似影响 翻译改进

Janel Hodge  1, Joshua P Bow, Kimberly S Plyler, V Kiran Vemuri, Ania Wisniecki, John D Salamone, Alexandros Makriyannis, Peter J McLaughlin

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  • 1 Department of Psychology, Edinboro University of Pennsylvania, 210 East Normal Street, Edinboro, PA 16444, USA.
  • DOI: 10.1016/j.bbr.2008.06.010 PMID: 18602425

    摘要 Ai翻译

    Cannabinoid CB1 inverse agonists such as rimonabant and AM 251 hold therapeutic promise as appetite suppressants, but the extent to which non-motivational factors contribute to their anorectic effects is not fully known. Examination of the behavioral satiety sequence (BSS) in rats, the orderly progression from eating to post-prandial grooming and then resting, has revealed that these compounds preserve the order of events but differ markedly from natural s... ...点击完成人机验证后继续浏览
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    期刊名:Behavioural brain research

    缩写:BEHAV BRAIN RES

    ISSN:0166-4328

    e-ISSN:1872-7549

    IF/分区:2.3/Q2

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    The cannabinoid CB1 receptor inverse agonist AM 251 and antagonist AM 4113 produce similar effects on the behavioral satiety sequence in rats