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Behavioural brain research. 2008 Nov 21;193(2):243-7. doi: 10.1016/j.bbr.2008.06.003 Q22.32025

The microinjection of AMPA receptor antagonist into the accumbens shell failed to change food intake, but reduced fear-motivated behaviour in free-feeding female rats

AMPA受体拮抗剂微注射到伏隔核壳核未能改变自由进食大鼠的摄食行为,但减少了恐惧驱动的行为 翻译改进

Isabel Cristina da Cunha  1, Aparecida Marcelino de Nazareth, Juliano Cordova Vargas, Adriana Ferraz, José Marino Neto, Marta Aparecida Paschoalini, Moacir Serralvo Faria

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  • 1 Department of Physiological Sciences, Centre of Biological Sciences, Federal University of Santa Catarina (UFSC), Campus Trindade, 88.040-900 Florianópolis, SC, Brazil.
  • DOI: 10.1016/j.bbr.2008.06.003 PMID: 18586053

    摘要 Ai翻译

    This study investigated the effect of the AMPA receptor antagonist 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX; 2.5 and 5.0 nmol/side) microinjected into the core and shell sub-regions of the accumbens (Acb) nucleus, on food intake and the level of anxiety in female rats. Bilateral microinjections of CNQX (5.0 nmol/side) into the Acb shell (AP, +1.08 to +2.04), but not into the Acb core, induced an anxiolytic-like effect in relation to rats microinjected wi... ...点击完成人机验证后继续浏览
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    期刊名:Behavioural brain research

    缩写:BEHAV BRAIN RES

    ISSN:0166-4328

    e-ISSN:1872-7549

    IF/分区:2.3/Q2

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    The microinjection of AMPA receptor antagonist into the accumbens shell failed to change food intake, but reduced fear-motivated behaviour in free-feeding female rats