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Behavioural brain research. 2008 Nov 21;193(2):230-4. doi: 10.1016/j.bbr.2008.06.001 Q22.32025

Oligomers of the amyloid-beta protein disrupt working memory: confirmation with two behavioral procedures

寡聚体淀粉样蛋白-β破坏工作记忆:两种行为程序的验证结果 翻译改进

Alan Poling  1, Kineta Morgan-Paisley, John J Panos, Eun-Mee Kim, Eugene O'Hare, James P Cleary, Sylvain Lesné, Karen H Ashe, Matthew Porritt, Lisa E Baker

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  • 1 Department of Psychology, Western Michigan University, Kalamazoo, MI 49008, USA. alan.poling@wmich.edu
  • DOI: 10.1016/j.bbr.2008.06.001 PMID: 18585407

    摘要 Ai翻译

    Converging lines of evidence suggest that oligomers of amyloid-beta play a role in the cognitive impairment characteristic of Alzheimer's disease, but only three studies have provided experimental evidence of such impairment. To provide additional information about the effects of these oligomers on memory, the present study examined the memory of groups of rats exposed to ICV injections of the culture media (CM) of Chinese Hamster Ovary cells that were (7P... ...点击完成人机验证后继续浏览
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    期刊名:Behavioural brain research

    缩写:BEHAV BRAIN RES

    ISSN:0166-4328

    e-ISSN:1872-7549

    IF/分区:2.3/Q2

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    Oligomers of the amyloid-beta protein disrupt working memory: confirmation with two behavioral procedures