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Gabapentin: a Ca2+ channel alpha 2-delta ligand far beyond epilepsy therapy

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Gabapentin is an antiepileptic drug (AED) by design expected to mimic the action of the neurotransmitter gamma-aminobutyric acid (GABA). However, its principal proposed mechanism of action is the interaction with the alpha 2-delta subunit of L-type voltage-reg... ...