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Behavioural brain research. 2008 Oct 10;192(2):264-8. doi: 10.1016/j.bbr.2008.04.011 Q22.32025

Hippocampal NMDA receptors are necessary for auditory trace fear conditioning measured with conditioned hypoalgesia in rats

大鼠听觉延缓型恐惧条件反射测量中海马区N-甲基-D天冬氨酸受体必不可少 翻译改进

Dong-Oh Seo  1, Min-Hee Pang, Maeng-Sik Shin, Hyun-Taek Kim, June-Seek Choi

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  • 1 Department of Psychology, Korea University, 5-1 Anam-Dong, Seongbuk-Gu, Seoul, 136-701, Republic of Korea.
  • DOI: 10.1016/j.bbr.2008.04.011 PMID: 18514922

    摘要 Ai翻译

    We tested whether N-methyl-D-aspartate (NMDA) receptors in the dorsal hippocampus (DH) are critical for the acquisition of trace fear conditioning using conditioned hypoalgesia (CHA), decrease in pain reactivity, as the conditioned response (CR) instead of commonly used freezing. Infusions of the NMDA receptor antagonist, DL-2-amino-5-phosphonovaleric acid (APV) into DH prior to conditioning resulted in impaired CHA, measured with the radiant heat tail fli... ...点击完成人机验证后继续浏览
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    期刊名:Behavioural brain research

    缩写:BEHAV BRAIN RES

    ISSN:0166-4328

    e-ISSN:1872-7549

    IF/分区:2.3/Q2

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    Hippocampal NMDA receptors are necessary for auditory trace fear conditioning measured with conditioned hypoalgesia in rats