Structures of two archaeal diphthine synthases: insights into the post-translational modification of elongation factor 2
{{output}}
The target of diphtheria toxin is the diphthamide residue in translation elongation factor 2 (EF-2), which is generated by a three-step post-translational modification of a specific histidine residue in the EF-2 precursor. In the second modification step, an S... ...
