Risk assessment constitutes an essential component of genetic counseling and testing, and the genetic risk should be estimated as accurately as possible for individual and family decision making. All relevant information retrieved from population studies and pedigree and genetic testing enhances the accuracy of the assessment of an individual's genetic risk. This review will focus on the following general aspects implicated in risk assessment: the increasing genetic information regarding disease; complex traits versus Mendelian disorders; and the influence of the environment and disease susceptibility. The influence of these factors on risk assessment will be discussed.
Therapeutics and clinical risk management. 2005 Mar;1(1):15-20. doi: 10.2147/tcrm.1.1.15.53606
Principles in genetic risk assessment
基因风险评估原则 翻译改进
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DOI: 10.2147/tcrm.1.1.15.53606 PMID: 18360538
摘要 Ai翻译
Keywords：genetic risk assessment; principles
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