Modulation of activity by Arg407: structure of a fungal alpha-1,2-mannosidase in complex with a substrate analogue
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Class I alpha-mannosidases (glycoside hydrolase family GH47) play key roles in the maturation of N-glycans and the ER-associated degradation of unfolded glycoproteins. The 1.95 A resolution structure of a fungal alpha-1,2-mannosidase in complex with the substr... ...
