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Review Current opinion in neurobiology. 2007 Dec;17(6):665-71. doi: 10.1016/j.conb.2008.01.004 Q15.22025

Advances in understanding L-DOPA-induced dyskinesia

理解左旋多巴诱导的异动症方面的新进展 翻译改进

M A Cenci  1, H S Lindgren

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  • 1 Basal Ganglia Pathophysiology Unit, Department of Experimental Medical Science, Lund University, S-221 84 Lund, Sweden. Angela.Cenci_Nilsson@med.lu.se
  • DOI: 10.1016/j.conb.2008.01.004 PMID: 18308560

    摘要 Ai翻译

    The crucial role of dopamine (DA) in movement control is illustrated by the spectrum of motor disorders caused by either a deficiency or a hyperactivity of dopaminergic transmission in the basal ganglia. The degeneration of nigrostriatal DA neurons in Parkinson's disease causes poverty and slowness of movement. These symptoms are greatly improved by pharmacological DA replacement with L-3,4-dihydroxy-phenylalanine (L-DOPA), which however causes excessive i... ...点击完成人机验证后继续浏览
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    期刊名:Current opinion in neurobiology

    缩写:CURR OPIN NEUROBIOL

    ISSN:0959-4388

    e-ISSN:1873-6882

    IF/分区:5.2/Q1

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    Advances in understanding L-DOPA-induced dyskinesia