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Induction of COX-2 expression by acrolein in the rat model of hemorrhagic cystitis

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Aim: Acrolein (ACR) is a urinary metabolite of cyclophosphamide (CPS) and ifosfamide (IFS), which has been demonstrated to be the causative agent of hemorrhagic cystitis (HC), induced by these compounds. In this study, we investi... ...