Quantitative high-throughput screening using a live-cell cAMP assay identifies small-molecule agonists of the TSH receptor
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The thyroid-stimulating hormone (TSH; thyrotropin) receptor belongs to the glycoprotein hormone receptor subfamily of 7-transmembrane spanning receptors. TSH receptor (TSHR) is expressed mainly in thyroid follicular cells and is activated by TSH, which regulat... ...
