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Cathepsin V, but not cathepsins L, B and K, may release angiostatin-like fragments from plasminogen

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Abstract Cathepsin V is a lysosomal cysteine peptidase highly expressed in corneal epithelium; however, its function in the eye is still unknown. Here, we describe the capability of cathepsin V to hydrolyze plasminogen, which is also expressed in human cornea ... ...