Akt phosphorylates Connexin43 on Ser373, a "mode-1" binding site for 14-3-3
{{output}}
Connexin43 (Cx43) is a membrane-spanning protein that forms channels that bridge the gap between adjacent cells and this allows for the intercellular exchange of information. Cx43 is regulated by phosphorylation and by interacting proteins. "Mode-1" interactio... ...