Validation of a medium-throughput electrophysiological assay for KCNQ2/3 channel enhancers using IonWorks HT
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Enhancers of KCNQ channels are known to be effective in chronic pain models. To discover novel enhancers of KCNQ channels, the authors developed a medium-throughput electrophysiological assay by using the IonWorks platform. Screening of 20 CHO-K1 clones stably... ...