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Current opinion in neurobiology. 2007 Oct;17(5):581-6. doi: 10.1016/j.conb.2007.10.002 Q15.22025

Rapidly inducible, genetically targeted inactivation of neural and synaptic activity in vivo

快速诱发的、遗传靶向的活体神经元和突触失活技术 翻译改进

Dougal Tervo  1, Alla Y Karpova

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  • 1 Watson School of Biological Sciences, Cold Spring Harbor Laboratory, 1 Bungtown Rd, Cold Spring Harbor, NY 11724, United States.
  • DOI: 10.1016/j.conb.2007.10.002 PMID: 18054219

    摘要 Ai翻译

    Inducible and reversible perturbation of the activity of selected neurons in vivo is critical to understanding the dynamics of brain circuits. Several genetically encoded systems for rapid inducible neuronal silencing have been developed in the past few years offering an arsenal of tools for in vivo experiments. Some systems are based on ion-channels or pumps, others on G protein coupled receptors, and yet others on modified presynaptic proteins. Inducers ... ...点击完成人机验证后继续浏览
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    期刊名:Current opinion in neurobiology

    缩写:CURR OPIN NEUROBIOL

    ISSN:0959-4388

    e-ISSN:1873-6882

    IF/分区:5.2/Q1

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    Rapidly inducible, genetically targeted inactivation of neural and synaptic activity in vivo