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Review Current opinion in neurobiology. 2007 Oct;17(5):572-80. doi: 10.1016/j.conb.2007.10.001 Q15.22025

Combinatorial methods for refined neuronal gene targeting

精炼的神经元基因靶向的组合方法 翻译改进

Haojiang Luan  1, Benjamin H White

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  • 1 Laboratory of Molecular Biology, National Institute of Mental Health, NIH, 9000 Rockville Pike, Bethesda, MD 20892-3736, United States. luanh@mail.nih.gov
  • DOI: 10.1016/j.conb.2007.10.001 PMID: 18024005

    摘要 Ai翻译

    Methods for the selective and reproducible expression of genetically encoded tools in targeted subsets of cells are required to facilitate studies of neuronal development, connectivity, and function in living animals. In the absence of techniques for synthesizing promoters that target defined cell groups, current methods exploit the regulatory elements of endogenous genes to achieve specificity of transgene expression. However, single promoters often have ... ...点击完成人机验证后继续浏览
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    期刊名:Current opinion in neurobiology

    缩写:CURR OPIN NEUROBIOL

    ISSN:0959-4388

    e-ISSN:1873-6882

    IF/分区:5.2/Q1

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    Combinatorial methods for refined neuronal gene targeting