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Activation of the glutathione peroxidase 2 (GPx2) promoter by beta-catenin

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GPx2, formerly named gastrointestinal glutathione peroxidase, is highly expressed in the proliferative area of the intestinal crypt-to-villus axis and in Paneth cells. Additionally, GPx2 is transiently up-regulated during development of gastrointestinal adenoc... ...