Production of Slit2 LRR domains in mammalian cells for structural studies and the structure of human Slit2 domain 3
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Slit2 and Roundabout 1 (Robo1) provide a key ligand-receptor interaction for the navigation of commissural neurons during the development of the central nervous system. Slit2 is a large multidomain protein containing an unusual domain organization of four tand... ...