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Aryl hydrocarbon receptor splice variants in the dioxin-resistant rat: tissue expression and transactivational activity

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The AHR locus encodes the aryl hydrocarbon receptor (AHR), a transcriptional regulator of multiple drug-metabolizing enzymes and mediator of toxicity of dioxin-like chemicals. The Han/Wistar (Kuopio) rat strain (H/W) is remarkably resistant to lethal effects o... ...