The anti-apoptotic factor Che-1/AATF links transcriptional regulation, cell cycle control, and DNA damage response
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Che-1 is a RNA polymerase II binding protein involved in the transcriptional regulation of E2F target genes and in cell proliferation. Recently, it has been shown that Che-1 accumulates in cells responding to genotoxic agents such as Doxorubicin and ionizing r... ...
