Application of beta-lactamase enzyme complementation to the high-throughput screening of toll-like receptor signaling inhibitors
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We describe a successful application of beta-lactamase fragment complementation to high-throughput screening (HTS) for Toll-like receptor 4 (TLR4) signaling inhibitors. We developed a stable cell line, HeLa/CL3-4, expressing MyD88/Bla(a) and TLR4/Bla(b), in wh... ...
