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A specific box switches the cell fate determining activity of XOTX2 and XOTX5b in the Xenopus retina

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Background: Otx genes, orthologues of the Drosophila orthodenticle gene (otd), play crucial roles in vertebrate brain development. In the Xenopus eye, Xotx2 and Xotx5b promote bipolar and photoreceptor cell fates, respectively. T... ...