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Biotechnology and bioengineering. 2007 Dec 1;98(5):1029-42. doi: 10.1002/bit.21529 Q23.62025

Parametric study of a 6-column countercurrent solvent gradient purification (MCSGP) unit

六柱逆流溶剂梯度纯化(MCGSP)装置的参数研究 翻译改进

Lars Aumann  1, Guido Stroehlein, Massimo Morbidelli

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  • 1 ETH Zurich, Institute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, Hoenggerberg, HCI, 8093 Zurich, Switzerland.
  • DOI: 10.1002/bit.21529 PMID: 17595046

    摘要 Ai翻译

    The novel "multicolumn countercurrent solvent gradient purification" (MCSGP) process has been modeled for the purification of a polypeptide mixture characterized by a strong non-linear competitive adsorption isotherm. As a model system, the purification of an industrial polypeptide mixture containing 46% of the hormone calcitonin has been selected. The many impurities contained in the mixture have been lumped into three key impurities, which are selected a... ...点击完成人机验证后继续浏览
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    期刊名:Biotechnology and bioengineering

    缩写:BIOTECHNOL BIOENG

    ISSN:0006-3592

    e-ISSN:1097-0290

    IF/分区:3.6/Q2

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    Parametric study of a 6-column countercurrent solvent gradient purification (MCSGP) unit