Zoledronate inhibits alphavbeta3 and alphavbeta5 integrin cell surface expression in endothelial cells
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Zoledronate exhibits antiangiogenic properties in vitro and in vivo. Integrins alphavbeta3 and alphavbeta5 are involved in angiogenesis. Because zoledronate inhibits endothelial cell adhesion, the authors explored the hypothesis that it could alter these integ... ...
