High-throughput mass spectrometry screening for inhibitors of phosphatidylserine decarboxylase
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A high-throughput mass spectrometry assay to measure the catalytic activity of phosphatidylserine decarboxylase (PISD) is described. PISD converts phosphatidylserine to phosphatidylethanolamine during lipid synthesis. Traditional methods of measuring PISD acti... ...
